Miniaturized detection system for handheld PCR assays

James B. Richards; William J. Benett; Paul Stratton; Dean R. Hadley; Shanavaz L. Nasarabadi; Fred P. Milanovich

doi:10.1117/12.411713

29 December 2000 Miniaturized detection system for handheld PCR assays

James B. Richards, William J. Benett, Paul Stratton, Dean R. Hadley, Shanavaz L. Nasarabadi, Fred P. Milanovich

Proceedings Volume 4200, Biochemical and Biomolecular Sensing; (2000) https://doi.org/10.1117/12.411713
Event: Environmental and Industrial Sensing, 2000, Boston, MA, United States

Abstract

We have developed and delivered a four chamber, battery powered, handheld instrument referred to as the HANAA which monitors the polymerase chain reaction (PCR) process using a TaqMan based fluorescence assay. The detection system differs form standard configurations in two essential ways. First, the size is miniaturized, with a combined cycling and optics plug-in module for a duplex assay begin about the size of a small box of matches. Second, the detection/analysis system is designed to call a positive sample in real time.

Citation Download Citation

James B. Richards, William J. Benett, Paul Stratton, Dean R. Hadley, Shanavaz L. Nasarabadi, and Fred P. Milanovich "Miniaturized detection system for handheld PCR assays", Proc. SPIE 4200, Biochemical and Biomolecular Sensing, (29 December 2000); https://doi.org/10.1117/12.411713

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