Laser-induced fluorescence spectroscopy (LFS): detection of unstable thrombogenic atherosclerotic plaque formation in a rabbit model: a first-look diagnostic approach

Alexander M. Christov; Erbin Dai M.D.; Maria Drangova; Liying Liu; George S. Abela M.D.; Piers Nash; Grant McFadden; Alexandra Lucas

doi:10.1117/12.409329

16 November 2000 Laser-induced fluorescence spectroscopy (LFS): detection of unstable thrombogenic atherosclerotic plaque formation in a rabbit model: a first-look diagnostic approach

Alexander M. Christov, Erbin Dai M.D., Maria Drangova, Liying Liu, George S. Abela M.D., Piers Nash, Grant McFadden, Alexandra Lucas

Author Affiliations +

Proceedings Volume 4161, Optical Biopsy and Tissue Optics; (2000) https://doi.org/10.1117/12.409329
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Many approaches to imaging of unstable plaque have been applied to detect vascular thrombosis and occlusion with only moderate success. LFS detected significant and specific changes in thrombogenic plaque in a rabbit model. Fluorescence emission intensity analysis of structural characteristics may provide an optical diagnostic technique for early recognition of unstable coronary syndromes.

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Alexander M. Christov, Erbin Dai M.D., Maria Drangova, Liying Liu, George S. Abela M.D., Piers Nash, Grant McFadden, and Alexandra Lucas "Laser-induced fluorescence spectroscopy (LFS): detection of unstable thrombogenic atherosclerotic plaque formation in a rabbit model: a first-look diagnostic approach", Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); https://doi.org/10.1117/12.409329

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