Laser soldering of cuts in rat skin using fiber optic temperature-controlled system

D. Simhon; Avi Ravid; Marissa Halpern M.D.; Inci F. Cilesiz; Tamar Brosh; Noam Kariv; A. Leviav; Abraham Katzir

doi:10.1117/12.413809

19 January 2001 Laser soldering of cuts in rat skin using fiber optic temperature-controlled system

D. Simhon, Avi Ravid, Marissa Halpern M.D., Inci F. Cilesiz, Tamar Brosh, Noam Kariv, A. Leviav, Abraham Katzir

Proceedings Volume 4158, Biomonitoring and Endoscopy Technologies; (2001) https://doi.org/10.1117/12.413809
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Background and objectives: Laser soldering of tissues is based on the application of a biological solder on the approximated edges of a cut. Our goal was to use laser soldering for sealing cuts in skin under temperature feedback control and compare the results with ones obtained using standard sutures. Materials and methods: Albumin solder was applied onto the approximated edges of cuts created in rat skin. A fiberoptic system was used to deliver the radiation of a CO₂ laser, to heat a spot near the cut edges, and to control the temperature. Laser soldering was carried out, spot by spot, where the temperature at each spot was kept at 65-70 degree(s)C for 10 seconds. Results: The tensile strength of laser-soldered cuts was measured after 3-28 days postoperatively and was found comparable to that of sutured cuts. Histopathological studies showed no thermal damage and less inflammatory reaction than that caused by standard sutures. Conclusions: Temperature controlled laser soldering of cuts in rat skin gave strong bonding. The cosmetic and histological results were very good, in comparison to those of standard sutures.

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D. Simhon, Avi Ravid, Marissa Halpern M.D., Inci F. Cilesiz, Tamar Brosh, Noam Kariv, A. Leviav, and Abraham Katzir "Laser soldering of cuts in rat skin using fiber optic temperature-controlled system", Proc. SPIE 4158, Biomonitoring and Endoscopy Technologies, (19 January 2001); https://doi.org/10.1117/12.413809

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