Noninvasive fluorescence-based instrumentation for cancer and precancer detection and screening

Robert R. Alfano; Alvin Katz

doi:10.1117/12.382035

11 April 2000 Noninvasive fluorescence-based instrumentation for cancer and precancer detection and screening

Robert R. Alfano, Alvin Katz

Proceedings Volume 3913, In-Vitro Diagnostic Instrumentation; (2000) https://doi.org/10.1117/12.382035
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

In this paper, we review our research in the use of UV and visible native fluorescence emission and excitation spectroscopy for the detection of cancer and precancer. We discuss some of the spectroscopic signatures indicative of the presence of cancer and precancer. We describe three generations of instruments being developed to extent optical biopsy technology into the clinical environment as both a screening tool and as a diagnostic aide suitable for gynecological, gastro-intestinal tract, oral cavity, brain and breast.

Citation Download Citation

Robert R. Alfano and Alvin Katz "Noninvasive fluorescence-based instrumentation for cancer and precancer detection and screening", Proc. SPIE 3913, In-Vitro Diagnostic Instrumentation, (11 April 2000); https://doi.org/10.1117/12.382035

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