Synchrotron FTIR microspectroscopy of Alzheimer's diseased brain tissue at the SRC beamline

Pam S. Bromberg; Kathleen M. Gough; Mandy Ogg; M. R. Del Bigio; Robert Julian

doi:10.1117/12.366636

25 October 1999 Synchrotron FTIR microspectroscopy of Alzheimer's diseased brain tissue at the SRC beamline

Pam S. Bromberg, Kathleen M. Gough, Mandy Ogg, M. R. Del Bigio, Robert Julian

Proceedings Volume 3775, Accelerator-based Sources of Infrared and Spectroscopic Applications; (1999) https://doi.org/10.1117/12.366636
Event: SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, 1999, Denver, CO, United States

Abstract

Alzheimer's Disease is a neurodegenerative disorder marked by progressive cognitive decline. AD presents with many of the same clinical symptoms as senile dementia, but the diagnosis of AD must be confirmed by post-mortem examination of the morphological and histopathological features of the brain. The two classical lesions found in the cortical and hippocampal regions of the brain are the (beta) -amyloid- bearing neuritic plaques and the intraneuronal neurofibrillary tangles.

Citation Download Citation

Pam S. Bromberg, Kathleen M. Gough, Mandy Ogg, M. R. Del Bigio, and Robert Julian "Synchrotron FTIR microspectroscopy of Alzheimer's diseased brain tissue at the SRC beamline", Proc. SPIE 3775, Accelerator-based Sources of Infrared and Spectroscopic Applications, (25 October 1999); https://doi.org/10.1117/12.366636

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