Human thyroid specimen imaging by fluorescent x-ray computed tomography with synchrotron radiation

Tohoru Takeda; Quanwen Yu; Toru Yashiro; Tetsuya Yuasa; Yasuo Hasegawa; Yuji Itai; Takao Akatsuka

doi:10.1117/12.363728

22 September 1999 Human thyroid specimen imaging by fluorescent x-ray computed tomography with synchrotron radiation

Tohoru Takeda, Quanwen Yu, Toru Yashiro, Tetsuya Yuasa, Yasuo Hasegawa, Yuji Itai, Takao Akatsuka

Proceedings Volume 3772, Developments in X-Ray Tomography II; (1999) https://doi.org/10.1117/12.363728
Event: SPIE's International Symposium on Optical Science, Engineering, and Instrumentation, 1999, Denver, CO, United States

Abstract

Fluorescent x-ray computed tomography (FXCT) is being developed to detect non-radioactive contrast materials in living specimens. The FXCT system consists of a silicon (111) channel cut monochromator, an x-ray slit and a collimator for fluorescent x ray detection, a scanning table for the target organ and an x-ray detector for fluorescent x-ray and transmission x-ray. To reduce Compton scattering overlapped on the fluorescent K(alpha) line, incident monochromatic x-ray was set at 37 keV. The FXCT clearly imaged a human thyroid gland and iodine content was estimated quantitatively. In a case of hyperthyroidism, the two-dimensional distribution of iodine content was not uniform, and thyroid cancer had a small amount of iodine. FXCT can be used to detect iodine within thyroid gland quantitatively and to delineate its distribution.

Citation Download Citation

Tohoru Takeda, Quanwen Yu, Toru Yashiro, Tetsuya Yuasa, Yasuo Hasegawa, Yuji Itai, and Takao Akatsuka "Human thyroid specimen imaging by fluorescent x-ray computed tomography with synchrotron radiation", Proc. SPIE 3772, Developments in X-Ray Tomography II, (22 September 1999); https://doi.org/10.1117/12.363728

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