Fluorescence endoscopic imaging for evaluation of gastric mucosal blood flow: a preliminary study

Nicolas Bocquillon; Serge R. Mordon; D. Mathieu; Vincent Maunoury M.D.; Xavier-Marie Marechal; Remi Neviere; Francis Wattel; Claude Chopin

doi:10.1117/12.339193

12 February 1999 Fluorescence endoscopic imaging for evaluation of gastric mucosal blood flow: a preliminary study

Nicolas Bocquillon, Serge R. Mordon, D. Mathieu, Vincent Maunoury M.D., Xavier-Marie Marechal, Remi Neviere, Francis Wattel, Claude Chopin

Author Affiliations +

Proceedings Volume 3567, Optical and Imaging Techniques for Biomonitoring IV; (1999) https://doi.org/10.1117/12.339193
Event: BiOS Europe '98, 1998, Stockholm, Sweden

Abstract

Microcirculatory disorders of the gastrointestinal tract appear to be a major compound of the multiple organ dysfunction syndrome secondary to sepsis or septic shock. A better analysis of mucosal hypoperfusion in critically ill patients with sepsis may be helpful for the comprehension of this high mortality-associated syndrome. Fluorescence endoscopy has been recognized as a non-invasive method for both spatial and temporal evaluation of gastrointestinal mucosal perfusion. We performed this imaging technique during routine gastric endoscopy in patients with sepsis criteria. The study included gastric observation and appearance time of gastric fluorescence after an intravenous 10% sodium - fluorescein bolus. Qualitative analysis of high fluorescence areas was compared with mucosal blood flow measurements by laser - Doppler flowmetry. We concluded that the fluorescence endoscopic imaging in critically ill patients with sepsis may reveal spacial and temporal differences in the mucosal microcirculation distribution.

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Nicolas Bocquillon, Serge R. Mordon, D. Mathieu, Vincent Maunoury M.D., Xavier-Marie Marechal, Remi Neviere, Francis Wattel, and Claude Chopin "Fluorescence endoscopic imaging for evaluation of gastric mucosal blood flow: a preliminary study", Proc. SPIE 3567, Optical and Imaging Techniques for Biomonitoring IV, (12 February 1999); https://doi.org/10.1117/12.339193

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KEYWORDS

Luminescence

Endoscopy

Blood circulation

Blood

Angiography

Digital video recorders

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