Scanned probe microscope for biological applications

Vil B. Baiburin; Nikolai P. Konnov; Anatolyi A. Shcherbakov; Alina N. Malakhaeva; Svetlana P. Zadnova; Yuri P. Volkov

doi:10.1117/12.297976

29 December 1997 Scanned probe microscope for biological applications

Vil B. Baiburin, Nikolai P. Konnov, Anatolyi A. Shcherbakov, Alina N. Malakhaeva, Svetlana P. Zadnova, Yuri P. Volkov

Proceedings Volume 3197, Optical Biopsies and Microscopic Techniques II; (1997) https://doi.org/10.1117/12.297976
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

In our biophysical laboratory has been developed a new scanned probe microscope (SPM) for biological application. The SPM allows to investigate a biological samples' surface by means of three different near field microscopes: scanning tunneling microscope (STM), atomic force microscope (AFM) and near field scanning optical microscope (NSOM). The SPM is very rigid and can be operated in ordinary laboratory without any vibration isolation. The scanning area of the microscope is about 10 by 10 micrometers. Some different biological objects were visualized by means of the SPM viz. bacteria (E. Coli, plague, cholera, staphylococcus), macromolecules (DNA, plague proteins) and phage (T2).

Citation Download Citation

Vil B. Baiburin, Nikolai P. Konnov, Anatolyi A. Shcherbakov, Alina N. Malakhaeva, Svetlana P. Zadnova, and Yuri P. Volkov "Scanned probe microscope for biological applications", Proc. SPIE 3197, Optical Biopsies and Microscopic Techniques II, (29 December 1997); https://doi.org/10.1117/12.297976

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