Development of a probe for use with the Paterson lamp in photodynamic therapy (PDT) of the esophagus and colorectum

Joseph V. E. Roche; Colin Whitehurst; Peter Watt; James V. Moore; Neville Krasner M.D.

doi:10.1117/12.297851

22 December 1997 Development of a probe for use with the Paterson lamp in photodynamic therapy (PDT) of the esophagus and colorectum

Joseph V. E. Roche, Colin Whitehurst, Peter Watt, James V. Moore, Neville Krasner M.D.

Author Affiliations +

Proceedings Volume 3192, Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry, and Endoscopy; (1997) https://doi.org/10.1117/12.297851
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

The Paterson lamp is a convenient, low cost, portable, alternative light source to lasers for PDT. A multi- wavelength capability enables the clinician to vary the photosensitizer used. The Paterson lamp has been applied in the field of dermatology using a liquid light guide with distal optics for surface application. We now describe distal optics suitable for use with this light guide for intraluminal applications in the oesophagus and colorectum. The geometry of the site (oesophagus and colorectum) requires distal optics such as a cylindrical diffuser or a side fire diffuser. We have designed new cylindrical probes that diffuse light radially from the guide axis (cylindrical diffusion). The tips have a frosted glass surface that scatters and effectively couples light radially into the tissue. An acrylic spacer is placed over the diffuser to position the tissue at a constant diameter from the probe. This is held in position by a silicone sheath placed over the distal one meter. For use in the oesophagus, a channel, to facilitate intubation over a guide wire, is included. The diameter of the entire probe is 8.4 mm and the power output can be adjusted from 0 - 500 mW.

Citation Download Citation

Joseph V. E. Roche, Colin Whitehurst, Peter Watt, James V. Moore, and Neville Krasner M.D. "Development of a probe for use with the Paterson lamp in photodynamic therapy (PDT) of the esophagus and colorectum", Proc. SPIE 3192, Medical Applications of Lasers in Dermatology, Ophthalmology, Dentistry, and Endoscopy, (22 December 1997); https://doi.org/10.1117/12.297851

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available