Deformable anatomical templates for brachytherapy treatment planning in radiotherapy of cervical cancer

Gary E. Christensen; Jeffrey F. Williamson; K. S. C. Chao; Michael I. Miller; F. B. So; Michael W. Vannier M.D.

doi:10.1117/12.292779

20 October 1997 Deformable anatomical templates for brachytherapy treatment planning in radiotherapy of cervical cancer

Gary E. Christensen, Jeffrey F. Williamson, K. S. C. Chao, Michael I. Miller, F. B. So, Michael W. Vannier M.D.

Proceedings Volume 3168, Vision Geometry VI; (1997) https://doi.org/10.1117/12.292779
Event: Optical Science, Engineering and Instrumentation '97, 1997, San Diego, CA, United States

Abstract

This paper describes a new method to register serial, volumetric x-ray computed tomography (CT) data sets for tracking soft-tissue deformation caused by insertion of intracavity brachytherapy applicators to treat cervical cancer. 3D CT scans collected from the same patient with and without a brachytherapy applicator are registered to aid in computation of the radiation dose to tumor and normal tissue. The 3D CT image volume of pelvic anatomy with the applicator. Initial registration is accomplished by rigid alignment of the pelvic bones and non-rigid alignment of gray scale CT data and hand segmentations of the vagina, cervix, bladder, and rectum. A viscous fluid transformation model is used for non-rigid registration to allow for local, non-linear registration of the vagina, cervix, bladder, and rectum without disturbing the rigid registration of the bony pelvis and adjacent structures. Results are presented in which two 3D CT data sets of the same patient - imaged with and without a brachytherapy applicator - are registered.

Citation Download Citation

Gary E. Christensen, Jeffrey F. Williamson, K. S. C. Chao, Michael I. Miller, F. B. So, and Michael W. Vannier M.D. "Deformable anatomical templates for brachytherapy treatment planning in radiotherapy of cervical cancer", Proc. SPIE 3168, Vision Geometry VI, (20 October 1997); https://doi.org/10.1117/12.292779

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