Experimental and clinical studies of blood reaction to light irradiation

Tatyana A. Yakhno

doi:10.1117/12.266246

11 February 1997 Experimental and clinical studies of blood reaction to light irradiation

Tatyana A. Yakhno

Proceedings Volume 3053, Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies: International Workshop; (1997) https://doi.org/10.1117/12.266246
Event: International Workshop on Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies, 1996, Saratov, Russian Federation

Abstract

Experimental and clinical studies carried out with the help of optical, biochemical, potentiometric and EPR-methods showed that blood reaction to light irradiation is similar to that of nonequilibrium medium characterized by oscillating and multistationary regimes that makes it impossible to a priori predict the only possible reaction. The mechanism of biological effect of low-intensity light is realized through deviations in oxidation-reduction blood system balance due to selective activation of these or those key components which include, in particular, compounds containing Fe and Cu ions. Value and sign of these reactions are determined by the state of this system at each time moment and are nontrivially associated with the light of different wavelength ranges. A possibility to predict the reaction of the patient to phototherapy based on the results of preliminary irradiation of his blood in vitro is shown. The technique and laboratory criteria making it possible to predict directivity and efficiency of the patient's reaction to future-to-be irradiation (irrespective of the manner of irradiation) and to choose the required wavelength range providing for the optimal therapeutic effect at this particular time moment is worked out.

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Tatyana A. Yakhno "Experimental and clinical studies of blood reaction to light irradiation", Proc. SPIE 3053, Nonlinear Dynamics and Structures in Biology and Medicine: Optical and Laser Technologies: International Workshop, (11 February 1997); https://doi.org/10.1117/12.266246

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KEYWORDS

Blood

In vitro testing

Phototherapy

Plasma

Organisms

Resistance

Absorbance

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