Paper
18 August 1997 Noninvasive investigation of skin local hypothermia influence upon local oxygenation and hemoglobin concentration
Alexandre Yu. Douplik, Manfred D. Kessler, Yasuyuki Kakihana M.D., Alfons Krug
Author Affiliations +
Abstract
Functional evaluation of local hemoglobin concentration and hemoglobin oxygenation based on back scattering spectra from human skin in vivo have been obtained in visible range (502 - 628 nm) by a rapid microlightguide spectrometer (EMPHO II) with step 250 micrometer. Analysis of received results has shown that during local cooling there is two nearly simultaneous reactions: reduction of hemoglobin concentration and increase of hemoglobin oxygenation level. In a case when one has used previous heating of planning place for cooling, reduction of hemoglobin concentration is expressed higher by 22 - 33%.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Alexandre Yu. Douplik, Manfred D. Kessler, Yasuyuki Kakihana M.D., and Alfons Krug "Noninvasive investigation of skin local hypothermia influence upon local oxygenation and hemoglobin concentration", Proc. SPIE 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, (18 August 1997); https://doi.org/10.1117/12.280267
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KEYWORDS
Skin

Photodynamic therapy

Tissue optics

Blood

Laser tissue interaction

In vivo imaging

Spectroscopy

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