Autofluorescence of ocular tissues: an update of measurement techniques for research and diagnosis

Franco Docchio; Luigi Rovati

doi:10.1117/12.275096

26 May 1997 Autofluorescence of ocular tissues: an update of measurement techniques for research and diagnosis

Franco Docchio, Luigi Rovati

Proceedings Volume 2971, Ophthalmic Technologies VII; (1997) https://doi.org/10.1117/12.275096
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

Ophthalmic diagnosis through measurements of ocular tissues autofluorescence has recently reached its first clinical maturity. This technique is intrinsically non-invasive and, thanks to the availability of a new family of measuring instruments, is becoming reliable even if performed in a few seconds and is of no burden to the patient. Diagnostic methods based on ocular tissue autofluorescence could become important tools in the prevention of a number of diseases which may lead to blindness, and therefore have a great social impact. The present paper is intended to give, from one side, an update of the rationale concerning fluorophores in the eye and their absorption and fluorescence properties; from the other, it offers an overview of ophthalmic fluorescence techniques aimed at the detection, quantitation and discrimination of ocular autofluorescing substances, highlighting their usefulness as a diagnostic aid in the early detection and prevention of ocular diseases.

Citation Download Citation

Franco Docchio and Luigi Rovati "Autofluorescence of ocular tissues: an update of measurement techniques for research and diagnosis", Proc. SPIE 2971, Ophthalmic Technologies VII, (26 May 1997); https://doi.org/10.1117/12.275096

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