Photodynamic therapy of recurrent cancer of oral cavity

Eugeny Ph. Stranadko; Oleg K. Skobelkin; Nikolai A. Markichev; Michail V. Riabov

doi:10.1117/12.251934

23 September 1996 Photodynamic therapy of recurrent cancer of oral cavity

Eugeny Ph. Stranadko, Oleg K. Skobelkin, Nikolai A. Markichev, Michail V. Riabov

Proceedings Volume 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment; (1996) https://doi.org/10.1117/12.251934
Event: Photonics China '96, 1996, Beijing, China

Abstract

Photo dynamic therapy (PDT) with use of two Russian photosensitizers, photohem (hematoporphyrine derivative) in the dosage 1.5-5.0 mg/kg of body weight and photosense in the dosage 0.5-1.5 mg/kg of body weight has been provided in 26 patients with spread recurrent tumors of oral cavity. During PDT power density has been from 50 to 1000 mW/cm². Light irradiation doses ranging from 50 to 600 J/cm². Therapeutic effect in term from 2 months to 3 years took place in 24 patients. In 18 cases complete resorption of tumor was achieved, in 6 cases, partial resorption. No effect was found in 2 cases. Our experience supposes that PDT appears to be a reasonable alternative to the traditional therapy of recurrent tumors of oral cavity.

Citation Download Citation

Eugeny Ph. Stranadko, Oleg K. Skobelkin, Nikolai A. Markichev, and Michail V. Riabov "Photodynamic therapy of recurrent cancer of oral cavity", Proc. SPIE 2887, Lasers in Medicine and Dentistry: Diagnostics and Treatment, (23 September 1996); https://doi.org/10.1117/12.251934

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