In-vivo measurement of phosphorus in bones of the hands: ten years of clinical experience

John A. Kalef-Ezra; Ioannis Hatzikonstantinou; Dimitrios C. Glaros; Seiichi Yasumura

doi:10.1117/12.267935

27 February 1997 In-vivo measurement of phosphorus in bones of the hands: ten years of clinical experience

John A. Kalef-Ezra, Ioannis Hatzikonstantinou, Dimitrios C. Glaros, Seiichi Yasumura

Proceedings Volume 2867, International Conference Neutrons in Research and Industry; (1997) https://doi.org/10.1117/12.267935
Event: Fifth International Conference on Applications of Nuclear Techniques: Neutrons in Research and Industry, 1996, Crete, Greece

Abstract

A facility was constructed for the in vivo measurement of phosphorus in the bones of the human hands. The technique is based on the detection of the delayed (gamma) -rays emitted from ²⁸Al produced via the ³¹P(n,(alpha) )²⁸Al reaction. The 4-min irradiation by two ²⁴¹Am-Be sources is followed by a 4-min counting of the induced activity with two Nal(Tl) detectors. The long-term in vivo precision of the measurements was found to be 2.8 percent and the effective dose is 50 (mu) Sv. To date, well over 1000 measurements have been carried out. The amount of phosphorus in hands in healthy adults was correlated with sex, age, height, forearm bone mineral content, bone mineral density in the spine, total body fat free mass and total body cell mass. Moreover, the measurement of phosphorus in the bones of the hands of patients provided answers to a number of clinical problems.

Citation Download Citation

John A. Kalef-Ezra, Ioannis Hatzikonstantinou, Dimitrios C. Glaros, and Seiichi Yasumura "In-vivo measurement of phosphorus in bones of the hands: ten years of clinical experience", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); https://doi.org/10.1117/12.267935

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