Paper
27 February 1997 In-vivo measurement of phosphorus in bones of the hands: ten years of clinical experience
John A. Kalef-Ezra, Ioannis Hatzikonstantinou, Dimitrios C. Glaros, Seiichi Yasumura
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Proceedings Volume 2867, International Conference Neutrons in Research and Industry; (1997) https://doi.org/10.1117/12.267935
Event: Fifth International Conference on Applications of Nuclear Techniques: Neutrons in Research and Industry, 1996, Crete, Greece
Abstract
A facility was constructed for the in vivo measurement of phosphorus in the bones of the human hands. The technique is based on the detection of the delayed (gamma) -rays emitted from 28Al produced via the 31P(n,(alpha) )28Al reaction. The 4-min irradiation by two 241Am-Be sources is followed by a 4-min counting of the induced activity with two Nal(Tl) detectors. The long-term in vivo precision of the measurements was found to be 2.8 percent and the effective dose is 50 (mu) Sv. To date, well over 1000 measurements have been carried out. The amount of phosphorus in hands in healthy adults was correlated with sex, age, height, forearm bone mineral content, bone mineral density in the spine, total body fat free mass and total body cell mass. Moreover, the measurement of phosphorus in the bones of the hands of patients provided answers to a number of clinical problems.
© (1997) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
John A. Kalef-Ezra, Ioannis Hatzikonstantinou, Dimitrios C. Glaros, and Seiichi Yasumura "In-vivo measurement of phosphorus in bones of the hands: ten years of clinical experience", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); https://doi.org/10.1117/12.267935
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KEYWORDS
Bone

Phosphorus

Minerals

In vivo imaging

Calcium

Sensors

Tissues

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