Measurements of light penetration into human tissues in vivo

Vladimir Iani; Johan Moan; Li Wei Ma

doi:10.1117/12.230985

31 January 1996 Measurements of light penetration into human tissues in vivo

Vladimir Iani, Johan Moan, Li Wei Ma

Proceedings Volume 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities; (1996) https://doi.org/10.1117/12.230985
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

A main factor to consider before photochemotherapy (PCT) is chosen to treat a tumor is whether sufficient fluences of light can reach the base of the tumor. The choice of optimal wavelengths for PCT should also be based on a knowledge of the optical penetration spectrum of the tumor. By means of a fiberoptic probe, adapted to a commercial fluorescence spectrometer, it is possible to measure the penetration depths of visible light into living, human tissues. We have performed such experiments, using the light from a 1000 W Xenon lamp. The light was guided from the lamp to the tissue by a perspex rod and the fluence rate penetrating different thickness of tissue was monitored by the fiberoptic probe. From penetration curves obtained at a number of wavelengths, it was possible to construct an accurate optical penetration spectrum of the tissue.

Citation Download Citation

Vladimir Iani, Johan Moan, and Li Wei Ma "Measurements of light penetration into human tissues in vivo", Proc. SPIE 2625, Photochemotherapy: Photodynamic Therapy and Other Modalities, (31 January 1996); https://doi.org/10.1117/12.230985

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available