Treatment of skin melanomas with the use of pulsed laser radiation

Konstantin G. Moskalik M.D.; Robert I. Wagner; Alexander P. Kozlov

doi:10.1117/12.209148

12 May 1995 Treatment of skin melanomas with the use of pulsed laser radiation

Konstantin G. Moskalik M.D., Robert I. Wagner, Alexander P. Kozlov

Proceedings Volume 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V; (1995) https://doi.org/10.1117/12.209148
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

The strong pulsed lasers radiation on the Neodim glass was used for the treatment of 265 patients with stage I skin melanoma. To 230 (86.4%) of them the treatment was carried out 5 years ago and even earlier. The duration of follow-up was from 1 to 22 years. The local recurrence of melanoma was diagnosed in 2 (0.75%) of these patients. Regional metastases developed in 44 (16.6%) patients, distant metastases--in 12 (4.5%) patients; in 1 (0.4%) patient the transport metastasis was revealed. More over, in patients to whom this type of treatment was carried out 5 years ago and even earlier regional metastases were diagnosed in 19.1% of cases, distant metastases--in 5.2% of cases, and transport metastases--in 0.4% of cases. 5-year survival rate of the patients made up 83.2%. In case of the I level of invasion (according to Clark classification) 100% of patients were alive for 5 years and even longer, in case of the II level of invasion this index made up 92.3%, in case of the III level--85.7%, and in case of the IV level--80.5%. In melanomas the thickness of which did not exceed 1.5 mm (according to Breslow classification) 5-year survival rate of the patients made up 96.7%, and in the tumors being from 1.51 mm to 4.5 mm thick this index mae up 80.0%. The strong pulsed lasers radiation is the effective method of treatment of plane or slightly elevated skin melanomas of the I-IV levels of invasion (Clark classification) the thickness of which is up to 4.5 mm according to Breslow.

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Konstantin G. Moskalik M.D., Robert I. Wagner, and Alexander P. Kozlov "Treatment of skin melanomas with the use of pulsed laser radiation", Proc. SPIE 2395, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems V, (12 May 1995); https://doi.org/10.1117/12.209148

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KEYWORDS

Melanoma

Skin

Pulsed laser operation

Radiation effects

Biopsy

Laser therapeutics

Head

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