Experience of application of nephelometry for the analyses of aggregational state of blood in a clinic of internal diseases

Alexander V. Priezzhev; Nikolai N. Firsov; Olga M. Ryaboshapka; Igor V. Sirko

doi:10.1117/12.180778

21 July 1994 Experience of application of nephelometry for the analyses of aggregational state of blood in a clinic of internal diseases

Alexander V. Priezzhev, Nikolai N. Firsov, Olga M. Ryaboshapka, Igor V. Sirko

Author Affiliations +

Proceedings Volume 2136, Biochemical Diagnostic Instrumentation; (1994) https://doi.org/10.1117/12.180778
Event: OE/LASE '94, 1994, Los Angeles, CA, United States

Abstract

It is well known that the hemorheological disturbances play an important role in the pathogenesis of many diseases. Rheological methods, aggregometry in particular, are efficient in the study of the role of the erythrocytes in the hemorheological disturbances. Wide application of aggregometry is limited because of the absence of the standard methods and devices. It should be noted that the generally accepted correlation between the aggregation state of blood and the variation of the light scattering intensity is not at all clear. We have worked out a system of informative parameters which can be distinguished when registering the backscattered light and use it for the microrheological diagnostics. In this paper we report on the application of the aggregometry method for the diagnostics of many diseases and present the statistically treated parameters of the erythrocytes aggregation.

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Alexander V. Priezzhev, Nikolai N. Firsov, Olga M. Ryaboshapka, and Igor V. Sirko "Experience of application of nephelometry for the analyses of aggregational state of blood in a clinic of internal diseases", Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); https://doi.org/10.1117/12.180778

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