Occupational glycol ether exposure: examinations to the evaluation of a limit value for biological monitoring of 2-ethoxyethanol and 2-ethoxyethyl acetate

Birgit Soehnlein; Karl Heinz Schaller; Juergen Angerer

doi:10.1117/12.140283

9 March 1993 Occupational glycol ether exposure: examinations to the evaluation of a limit value for biological monitoring of 2-ethoxyethanol and 2-ethoxyethyl acetate

Birgit Soehnlein, Karl Heinz Schaller, Juergen Angerer

Author Affiliations +

Proceedings Volume 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers; (1993) https://doi.org/10.1117/12.140283
Event: Environmental Sensing '92, 1992, Berlin, Germany

Abstract

Seventeen persons from a varnish production plant or the ceramic industry were examined for their excretion of 2-ethoxyacetic acid (EAA) in urine after occupational exposure to 2- ethoxyethanol (EE) or 2-ethoxyethyl acetate (EEAc). Sampling of urine was performed before and during an exposure-free weekend. On Friday post-shift a median value of 29,8 mg/l was determined for EAA in urine, on Monday morning of 10,7 mg/l. Based on the EAA elimination curves a medium half-life of 57,4 or 57,1 hours respectively was calculated. These values are considerably longer than values from literature (21 - 42 hours). As a consequence the German BAT value of 50 mg EAA per liter urine is only half as high as the currently discussed proposal for the American BEI value.

Citation Download Citation

Birgit Soehnlein, Karl Heinz Schaller, and Juergen Angerer "Occupational glycol ether exposure: examinations to the evaluation of a limit value for biological monitoring of 2-ethoxyethanol and 2-ethoxyethyl acetate", Proc. SPIE 1716, International Conference on Monitoring of Toxic Chemicals and Biomarkers, (9 March 1993); https://doi.org/10.1117/12.140283

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