Structural analysis of DNA oligomers in single crystals and in aqueous solutions by micro-FTIR and Raman spectroscopy

Heinz Fabian; W. Hoelzer; Dieter Naumann; H. Welfle; U. Heinemann

doi:10.1117/12.56445

1 March 1992 Structural analysis of DNA oligomers in single crystals and in aqueous solutions by micro-FTIR and Raman spectroscopy

Heinz Fabian, W. Hoelzer, Dieter Naumann, H. Welfle, U. Heinemann

Author Affiliations +

Proceedings Volume 1575, 8th Intl Conf on Fourier Transform Spectroscopy; (1992) https://doi.org/10.1117/12.56445
Event: Eighth International Conference on Fourier Transform Spectroscopy, 1991, Lubeck-Travemunde, Germany

Abstract

Being interested in the effects of base sequence and environmental conditions on the DNA structure, we have analyzed the solution and crystal structures of some G/C-rich DNA oligomers by vibrational spectroscopy. Here, we report on the analysis of the octamer d(GGGATCCC) and the decamer d(CCAGGCCTGG). Raman spectra were recorded on a Raman spectrometer as in, infrared spectra were measured with a Fourier transform infrared spectrophotometer Bruker IFS-66, for infrared measurements on crystals, the IFS-66 was coupled to an IR-microscope.

Citation Download Citation

Heinz Fabian, W. Hoelzer, Dieter Naumann, H. Welfle, and U. Heinemann "Structural analysis of DNA oligomers in single crystals and in aqueous solutions by micro-FTIR and Raman spectroscopy", Proc. SPIE 1575, 8th Intl Conf on Fourier Transform Spectroscopy, (1 March 1992); https://doi.org/10.1117/12.56445

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