The promise of nanomedicine in ovarian cancer treatment: a review and outlook

Kejun Wang

doi:10.1117/12.3013203

8 January 2024 The promise of nanomedicine in ovarian cancer treatment: a review and outlook

Kejun Wang

Proceedings Volume 12924, Third International Conference on Biological Engineering and Medical Science (ICBioMed2023); 129243Y (2024) https://doi.org/10.1117/12.3013203
Event: 3rd International Conference on Biological Engineering and Medical Science (ICBioMed2023), 2023, ONLINE, United Kingdom

Abstract

Ovarian cancer stands as a principal contributor to cancer-associated mortality amongst women, posing a worldwide health issue. Current advancements in preventative, interventional, and therapeutic strategies, while significant, are often impeded by issues such as drug resistance, severe toxicity, and delayed diagnosis of the disease. In light of these hurdles, this manuscript probes the promising sphere of nanomedicine in addressing ovarian cancer, discussing both the present landscape of nanotechnology-anchored therapies and their prospective implications. Nanomedicine presents singular benefits for drug transport, thus emerging as a potent instrument in this scenario. This manuscript further delves into the study of diverse nanoparticles (NPs) designed for regulated drug delivery and accentuates the breakthroughs in RNAcentric nanodrugs that target select proteins, such as the CKAP5 protein, which have demonstrated substantial outcomes in recent investigations. While the prospect is encouraging, certain obstacles must be confronted for more extensive application of nanomedicine in ovarian cancer therapeutics, including complications connected to drug delivery regulation, toxicity, and specificity. These issues underscore the necessity for sustained scientific investigation and ingenuity in this discipline. This manuscript provides an exhaustive overview, referencing current research, pinpointing potential impediments, and proffering direction for impending research and application of nanomedicine in the combat against ovarian cancer. The objective is to spark novel research trajectories and expedite the evolution of more efficacious, precision-targeted therapies for ovarian cancer.

(2024) Published by SPIE. Downloading of the abstract is permitted for personal use only.

Citation Download Citation

Kejun Wang "The promise of nanomedicine in ovarian cancer treatment: a review and outlook", Proc. SPIE 12924, Third International Conference on Biological Engineering and Medical Science (ICBioMed2023), 129243Y (8 January 2024); https://doi.org/10.1117/12.3013203

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KEYWORDS

Nanomedicine

Ovarian cancer

Cancer

Nanoparticles

Tumors

Therapeutics

Proteins

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