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One common approach to separatingmelanin and hemoglobin distribution from a color image is Independent Component Analysis (ICA). In this study, we propose a method based on deep learning to automatically detect suitable areas for successful facial pigmentation analysis. To do that, three deep learning models are utilized for segmentation and localization to offer a candidate region for ICA. The experiment was conducted using cross-polarized facial images selected from 200 subjects, and results showed that the deep learning-guided ICA can effectively identify regions of hyperpigmentation and successfully separate melanin and hemoglobin maps for evaluation.
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