Philipp Rauschendorfer,1,2 Andrew Thrapp,2 Guillermo J. Tearney,2,3 Farouc A. Jaffer1,2
1Harvard Medical School (United States) 2Wellman Ctr. for Photomedicine, Massachusetts General Hospital (United States) 3Massachusetts General Hospital (United States)
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We describe a substantially improved NIRF-IVUS imaging system to overcome current technical limitations. We have implemented a hybrid rotary joint capable of rotational speeds up to 6,000rpm and developed a NIRF-IVUS imaging catheter with a robust dual-layer drive shaft and a reduced rigid length of 2mm with a catheter size <3.6F. NIRF-IVUS processing software was also improved by implementing a high-speed acquisition trigger and data streaming for fast recording speeds. NIRF-IVUS imaging at speeds of at least 30 fps in phantoms and in vivo arterial disease models will demonstrate the unique capabilities of IVUS-NIRF imaging of plaque pathobiology.
Philipp Rauschendorfer,Andrew Thrapp,Guillermo J. Tearney, andFarouc A. Jaffer
"High-speed intravascular NIRF-IVUS imaging for the assessment of atherosclerosis in coronary-sized arteries", Proc. SPIE 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024, 1281911 (13 March 2024); https://doi.org/10.1117/12.3009997
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Philipp Rauschendorfer, Andrew Thrapp, Guillermo J. Tearney, Farouc A. Jaffer, "High-speed intravascular NIRF-IVUS imaging for the assessment of atherosclerosis in coronary-sized arteries," Proc. SPIE 12819, Diagnostic and Therapeutic Applications of Light in Cardiology 2024, 1281911 (13 March 2024); https://doi.org/10.1117/12.3009997