Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom

Charly Caredda; Frédéric Lange; Ilias Tachtsidis; Bruno Montcel

doi:10.1117/12.2670746

21 August 2023 Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom

Charly Caredda, Frédéric Lange, Ilias Tachtsidis, Bruno Montcel

Author Affiliations +

Proceedings Volume 12628, Diffuse Optical Spectroscopy and Imaging IX; 126280Q (2023) https://doi.org/10.1117/12.2670746
Event: European Conferences on Biomedical Optics, 2023, Munich, Germany

Abstract

Optical imaging is a non-invasive technique that is able to monitor hemodynamic and metabolic responses during neurosurgery. However, a robust quantification is complicated to perform. To overcome this issue, phantoms that mimic biological tissues are required for the development of imaging systems in order to reach a true standardization. In this work, we explore the possibility to use a combined liquid blood phantom with cytochrome contained yeast to evaluate the reliability of hyperspectral imaging to measure oxygenation and metabolic changes. This phantom can be used to verify the reliability of intraoperative optical setups before moving on to clinical application.

Citation Download Citation

Charly Caredda, Frédéric Lange, Ilias Tachtsidis, and Bruno Montcel "Evaluation of hyperspectral imaging measurements of changes in hemoglobin oxygenation and oxidation of cytochrome-c-oxidase using a liquid blood phantom", Proc. SPIE 12628, Diffuse Optical Spectroscopy and Imaging IX, 126280Q (21 August 2023); https://doi.org/10.1117/12.2670746

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