Glucagon-like peptide 1 receptor agonists in the treatment of type II diabetes

Xi Chen

doi:10.1117/12.2669050

24 March 2023 Glucagon-like peptide 1 receptor agonists in the treatment of type II diabetes

Xi Chen

Proceedings Volume 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022); 126114F (2023) https://doi.org/10.1117/12.2669050
Event: International Conference on Biological Engineering and Medical Science (ICBioMed2022), 2022, Oxford, United Kingdom

Abstract

Type 2 diabetes mellitus (T2D) is a chronic metabolic disease that have huge number of patients worldwide. Researches to T2D treatments will benefit many patients. T2D has been researched for over a century and the drugs used to treat it are becoming more effective every year. In current T2D treatments, Glucagon-like peptide 1 receptor agonist(GLP-1 RA)are a popular research direction. This review is intended to introduce 6 kinds of classic treatment including insulins, biguanides, sulphonylureas,GLP-1 RA, thiazolidinediones(TZD), Sodium-glucose co-transport protein(SGLT-2) and two kinds of latest treatment including new drug tirzepatide and combination therapy of T2D and highlight the mechanism as well as the safety profile of glucagon-like peptide-1 receptor agonists. Then present three kinds of medicine including Oral drugs with high convenience and high safety, multi-targeted drugs therapy which are more efficient and a new approach to treat T2D called gut microbiota therapy will all be potential research directions.

Citation Download Citation

Xi Chen "Glucagon-like peptide 1 receptor agonists in the treatment of type II diabetes", Proc. SPIE 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114F (24 March 2023); https://doi.org/10.1117/12.2669050

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