The structure of lentinan and its effects on immunomodulation, antitumour, and antiviral

Xiaorong Jin

doi:10.1117/12.2669637

24 March 2023 The structure of lentinan and its effects on immunomodulation, antitumour, and antiviral

Xiaorong Jin

Proceedings Volume 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022); 126114C (2023) https://doi.org/10.1117/12.2669637
Event: International Conference on Biological Engineering and Medical Science (ICBioMed2022), 2022, Oxford, United Kingdom

Abstract

Lentinan is a natural polymer extracted from high quality shiitake seeds, and its biological activity has received increasing attention with the development of modern molecular biology. The complex chemical structure of lentinan has a great influence on its biological activity, and in this paper, its structure is divided into primary structure and stereospecific structure respectively. In addition, we can enhance the biological activity of lentinan by structural modification. As one of the most promising drug resources, lentinan have strong immunomodulatory, antitumour and antiviral activities and are widely used as clinical adjuvant therapy for tumours. Lentinan do not kill tumour cells directly, but exert their anti-tumour effects through three main pathways by inducing biological responses in the body. In addition, lentinan can significantly improve the dysbiosis of intestinal flora while enhancing its immune function, and can be intensively studied as a microecological modulator with immunostimulatory functions.

Citation Download Citation

Xiaorong Jin "The structure of lentinan and its effects on immunomodulation, antitumour, and antiviral", Proc. SPIE 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126114C (24 March 2023); https://doi.org/10.1117/12.2669637

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