Earlier diagnosis of Alzheimer’s disease by identifying risk factors and utilizing biomarkers

Jianzhou Xu

doi:10.1117/12.2669022

24 March 2023 Earlier diagnosis of Alzheimer’s disease by identifying risk factors and utilizing biomarkers

Jianzhou Xu

Proceedings Volume 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022); 1261149 (2023) https://doi.org/10.1117/12.2669022
Event: International Conference on Biological Engineering and Medical Science (ICBioMed2022), 2022, Oxford, United Kingdom

Abstract

As the most common dementia, Alzheimer’s disease, has brought burden to millions to people, and will continue to do so in the coming decades. Patients and their families are suffering from this uncurable disease. Apart from developing treatments for AD, improving the diagnosis by making it earlier is also significant to the patients and society. Identifying the risk factors for AD and utilizing the biomarkers to examine AD are perhaps two strategies to enable early diagnosis. This paper has reviewed current research and summarized the existing proposed risk factors and biomarkers from both CSF and serum. The risk factors include cardiovascular diseases, lifestyle, and genetic predisposition, which may support identifying the people with higher risks of developing AD. Those higher-risk groups should be encouraged to participate in AD evaluation earlier. Certain biomarkers from CSF and serum may yield indicative results about AD diagnosis, which have the potential to be part of a more routine examination program.

Citation Download Citation

Jianzhou Xu "Earlier diagnosis of Alzheimer’s disease by identifying risk factors and utilizing biomarkers", Proc. SPIE 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 1261149 (24 March 2023); https://doi.org/10.1117/12.2669022

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KEYWORDS

Alzheimer's disease

Cardiovascular disorders

Genetics

Diagnostics

Neurological disorders

Brain

Brain diseases

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