A review of aberrant DNA methylation in bone marrow mesenchymal stromal cells: a new possible access of acute myeloid leukemia

Xiao Zhang

doi:10.1117/12.2669026

24 March 2023 A review of aberrant DNA methylation in bone marrow mesenchymal stromal cells: a new possible access of acute myeloid leukemia

Xiao Zhang

Author Affiliations +

Proceedings Volume 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022); 126112T (2023) https://doi.org/10.1117/12.2669026
Event: International Conference on Biological Engineering and Medical Science (ICBioMed2022), 2022, Oxford, United Kingdom

Abstract

The bone marrow mesenchymal stromal cells (BMMSCs) play a crucial role in the progression of acute myeloid leukemia (AML). However, the epigenetic landscape of AML patients' BMMSCs is currently not well understood. This paper reviewed the relationship between aberrant DNA methylation in BMMSCs and the development of AML based on the studies conducted by Roux and colleagues. The abnormal DNA methylation may represent a novel access point for AML, but it should be confirmed by additional research. This paper also provides suggestions for further research in this field.

Citation Download Citation

Xiao Zhang "A review of aberrant DNA methylation in bone marrow mesenchymal stromal cells: a new possible access of acute myeloid leukemia", Proc. SPIE 12611, Second International Conference on Biological Engineering and Medical Science (ICBioMed 2022), 126112T (24 March 2023); https://doi.org/10.1117/12.2669026

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