Integrated photoacoustic and ultrasonic endoscopy as a new tool for the early diagnosis of malignant biliary stricture

Sung Yong Han; KiSik Kim; Jin Young Youm; Minjae Kim; Sung Hee Park; Da Ye Jeon; Tae Beom Lee; Joon-Mo Yang; Dong Uk Kim

doi:10.1117/12.2625787

11 January 2022 Integrated photoacoustic and ultrasonic endoscopy as a new tool for the early diagnosis of malignant biliary stricture

Sung Yong Han, KiSik Kim, Jin Young Youm, Minjae Kim, Sung Hee Park, Da Ye Jeon, Tae Beom Lee, Joon-Mo Yang, Dong Uk Kim

Author Affiliations +

Proceedings Volume 12159, SPIE Advanced Biophotonics Conference (SPIE ABC 2021); 121590B (2022) https://doi.org/10.1117/12.2625787
Event: SPIE Advanced Biophotonics Conference (SPIE ABC 2021), 2021, Busan, Republic of Korea

Abstract

Correct diagnosis of biliary strictures is often challenging and requires imaging tests that allow physicians to see the bile duct. We developed a 3.38-mm outer diameter integrated PAE-EUS mini-probe, which featured the ability to provide an optical-resolution photoacoustic image as well as the traditional ultrasound image, and acquired the first in vivo PAEEUS images from the bile duct of a swine model by applying our dedicated probe sheath. As a microvasculature change in the walls of the biliary tract is expected to differ between benign and malignant lesions, the demonstrated technique could be a potential solution for the accurate diagnosis of biliary strictures.

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Sung Yong Han, KiSik Kim, Jin Young Youm, Minjae Kim, Sung Hee Park, Da Ye Jeon, Tae Beom Lee, Joon-Mo Yang, and Dong Uk Kim "Integrated photoacoustic and ultrasonic endoscopy as a new tool for the early diagnosis of malignant biliary stricture", Proc. SPIE 12159, SPIE Advanced Biophotonics Conference (SPIE ABC 2021), 121590B (11 January 2022); https://doi.org/10.1117/12.2625787

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