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An approach to visualization of the vascular bed with the possibility of assessing changes in blood filling and identifying diagnostically significant periodic changes in the signal by analyzing speckle images is proposed. The effect of singlet oxygen by direct excitation of an oxygen molecule by 1267 nm laser radiation on changes in the vascular bed parameters was studied using this approach.
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Irina N. Novikova, Mikhail V. Volkov, Lyubov V. Eratova, Denis I. Myalitsin, Viktor V. Dremin, "Direct optical generation of singlet oxygen in the regulation of vascular tone," Proc. SPIE 12147, Tissue Optics and Photonics II, 121470O (19 May 2022); https://doi.org/10.1117/12.2621491