Fiber-based optrodes: dual optical and electrical probe for optogenetics

Jelena Petrovic; Fred Lange; Dennis Hohlfeld

doi:10.1117/12.2621108

27 May 2022 Fiber-based optrodes: dual optical and electrical probe for optogenetics

Jelena Petrovic, Fred Lange, Dennis Hohlfeld

Proceedings Volume 12144, Biomedical Spectroscopy, Microscopy, and Imaging II; 1214402 (2022) https://doi.org/10.1117/12.2621108
Event: SPIE Photonics Europe, 2022, Strasbourg, France

Abstract

A microfabricated fiber-based optrode is presented, which performs simultaneous light delivery and electrophysiological recording. The fabrication approach assures minimal tissue damage during insertion. The device consists of a tapered fiber tip and three separate metal electrodes deposited on the cylindrical surface of the optical fiber. The tapered fiber tip enables precise light emission, as well as reliable light delivery to the targeted volume of brain tissue. Our custom precision fiber lateral and angular alignment setup allows us to fabricate a novel fiber based optrode with three separate equidistant metal electrodes along the fiber up to the fiber tip. Here we present our fabrication approach.

Conference Presentation

Citation Download Citation

Jelena Petrovic, Fred Lange, and Dennis Hohlfeld "Fiber-based optrodes: dual optical and electrical probe for optogenetics", Proc. SPIE 12144, Biomedical Spectroscopy, Microscopy, and Imaging II, 1214402 (27 May 2022); https://doi.org/10.1117/12.2621108

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