Wavelength modulation spectrometer using interband cascade laser for exhaled breath carbon monoxide measurement

Hongwei Chu; Yongjian Ma; Lei Yang

doi:10.1117/12.2606724

24 November 2021 Wavelength modulation spectrometer using interband cascade laser for exhaled breath carbon monoxide measurement

Hongwei Chu, Yongjian Ma, Lei Yang

Author Affiliations +

Proceedings Volume 12061, AOPC 2021: Infrared Device and Infrared Technology; 120611G (2021) https://doi.org/10.1117/12.2606724
Event: Applied Optics and Photonics China 2021, 2021, Beijing, China

Abstract

Exhaled breath analysis has attract growing attention as a promising noninvasive medical detection method. Carbon monoxide in human exhaled breath is of great value in the diagnosis of diseases, such as hematolysis and neonatal jaundice. However, conventional methods for the detection of CO was limited in practical application. In view of this, we have developed a highly sensitive system based on wavelength modulation spectroscopy by using an interband cascade laser at the optical wavelength of 4.71 μm. The temperature and pressure of gas example are extremely controlled by the proportional-integral-derivative control algorithm. As a proof of concept, the spectrometer was utilized to detect standard samples and real breath samples. The results show that the spectrometer has a good sensitivity with a detection limit of 3 ppb, and the concentration of CO in exhaled breath of non-smoking health people is flutuated little and not influenced significantly by the normal diet.

Citation Download Citation

Hongwei Chu, Yongjian Ma, and Lei Yang "Wavelength modulation spectrometer using interband cascade laser for exhaled breath carbon monoxide measurement", Proc. SPIE 12061, AOPC 2021: Infrared Device and Infrared Technology, 120611G (24 November 2021); https://doi.org/10.1117/12.2606724

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