Percutaneous coronary angioscopy with a new steerable microangioscope: experimental and early clinical results

Stephen R. Ramee M.D.; Christopher J. White M.D.; Juan E. Mesa M.D.; Joseph P. Murgo M.D.; Andrew Thomas Doyle; Colleen L. McQueen R.N.

doi:10.1117/12.17589

1 July 1990 Percutaneous coronary angioscopy with a new steerable microangioscope: experimental and early clinical results

Stephen R. Ramee M.D., Christopher J. White M.D., Juan E. Mesa M.D., Joseph P. Murgo M.D., Andrew Thomas Doyle, Colleen L. McQueen R.N.

Author Affiliations +

Proceedings Volume 1201, Optical Fibers in Medicine V; (1990) https://doi.org/10.1117/12.17589
Event: OE/LASE '90, 1990, Los Angeles, CA, United States

Abstract

We have developed a new, steerable microangioscope for performing percutaneous coronary angioscopy. The angioscopic catheter is made of polyethylene, contains a distal balloon for occlusion of blood flow during imaging, fits through an 8 Fr percutaneous coronary angioplasty (PTCA) guiding catheter and is steerable by means of a guidewire. Initial feasibility was demonstrated in animal studies involving both peripheral and coronary arteries. Angioscopic findings in normal vessels included normal endothelial surface, collateral blood flow, and side branches. Angioscopy was also performed after balloon denudation of the arteries, laser- assisted balloon angioplasty, and stent implantation. In early human clinical trials we have performed percutaneous angioscopy in six patients undergoing percutaneous coronary angioplasty without complications. Findings in these patients include atherosclerotic plaque, thrombus, and dissection. This new device has great potential for use in the research, diagnosis, and treatment of coronary atherosclerosis.

Citation Download Citation

Stephen R. Ramee M.D., Christopher J. White M.D., Juan E. Mesa M.D., Joseph P. Murgo M.D., Andrew Thomas Doyle, and Colleen L. McQueen R.N. "Percutaneous coronary angioscopy with a new steerable microangioscope: experimental and early clinical results", Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); https://doi.org/10.1117/12.17589

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KEYWORDS

Arteries

Angiography

Blood circulation

Laser therapeutics

Optical fibers

Medicine

Diagnostics

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