Richard B. Rosen,1 Justin V. Migacz,1 Oscar Otero-Marquez,1 Davis Zhou,1 Maria V. Castanos-Toral,1 Kara Rickford,1 Rebecca Zhou,1 Brian Murillo,1 Alexander Pinhas,1 Rishard Weitz,1 Nripun Sredar,1 Alfredo Dubrahttps://orcid.org/0000-0002-6506-9020,2 Toco Chui1
1New York Eye and Ear Infirmary of Mount Sinai (United States) 2Stanford Univ. (United States)
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Hyalocytes are resident macrophages residing in the vitreous cortex of the eye. They help maintain optical clarity, manage immunological threats, and respond to vascular insults. Recently, Castanos et al 2020 reported the ability to image these cells using clinical OCT and Hammer et al 2020 demonstrated their appearance using AO OCT. In this study we demonstrate the use of quad detection AO SLO imaging combined with clinical en face OCT in healthy human subjects to observe the dynamic morphological changes and the variable motility of these cells above the retinal surface over extended time intervals.
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Richard B. Rosen, Justin V. Migacz, Oscar Otero-Marquez, Davis Zhou, Maria V. Castanos-Toral, Kara Rickford, Rebecca Zhou, Brian Murillo, Alexander Pinhas, Rishard Weitz, Nripun Sredar, Alfredo Dubra, Toco Chui, "Dynamic imaging of vitreous cortex hyalocytes using adaptive optics scanning light ophthalmoscopy in human subjects," Proc. SPIE 11941, Ophthalmic Technologies XXXII, 1194103 (7 March 2022); https://doi.org/10.1117/12.2610678