Study on the light transmission and photothermal conversion of nanosecond laser pulse with brain using multiple physical field coupling

Jiahao Zeng; Ao Teng; Qianxiang Wan; Hongyu Zhang; Shangkun Hou; Xianlin Song

doi:10.1117/12.2612460

14 November 2021 Study on the light transmission and photothermal conversion of nanosecond laser pulse with brain using multiple physical field coupling

Jiahao Zeng, Ao Teng, Qianxiang Wan, Hongyu Zhang, Shangkun Hou, Xianlin Song

Author Affiliations +

Proceedings Volume 11914, SPIE Future Sensing Technologies 2021; 119140U (2021) https://doi.org/10.1117/12.2612460
Event: SPIE Future Sensing Technologies, 2021, Online Only

Abstract

Photoacoustic imaging technology is an emerging functional imaging method in the field of biomedical applications. It combines the light absorption characteristics of tissues and ultrasonic detection, and has the advantages of strong contrast, high sensitivity, and deep imaging depth. Light absorption and heat transfer are important processes of photoacoustic effect. Therefore, this article uses the finite element software COMSOL Multiphysics to study the photothermal effect of the interaction between laser pulses and mouse brain tissue. In COMSOL, a laser with a pulse width of 5ns is used as the excitation light source. The coefficient form partial differential equation module, the biological heat transfer module, etc. are used to simulate the light transmission and light-to-heat conversion process in the photoacoustic imaging of rat brain tissue. From this we can explore the photothermal effect produced when the laser interacts with biological tissues.

Citation Download Citation

Jiahao Zeng, Ao Teng, Qianxiang Wan, Hongyu Zhang, Shangkun Hou, and Xianlin Song "Study on the light transmission and photothermal conversion of nanosecond laser pulse with brain using multiple physical field coupling", Proc. SPIE 11914, SPIE Future Sensing Technologies 2021, 119140U (14 November 2021); https://doi.org/10.1117/12.2612460

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available