Nanoplasmonic drill for optical injection

Ancheng Da; Jacob Krach; Yanan Chu; Yunbo Liu; Somin Eunice Lee

doi:10.1117/12.2578373

8 March 2021 Nanoplasmonic drill for optical injection

Ancheng Da, Jacob Krach, Yanan Chu, Yunbo Liu, Somin Eunice Lee

Proceedings Volume 11661, Plasmonics in Biology and Medicine XVIII; 116610N (2021) https://doi.org/10.1117/12.2578373
Event: SPIE BiOS, 2021, Online Only

Abstract

Gold nanoparticles are ideal tools for cargo transportation. However, injection of nanoparticles into cells remains difficult. Current method utilizes laser light to heat up the particles and the surrounding media to create shock wave or air bubble to push the particle into the cells. However, high temperatures may result in cell and/or cargo damage. To solve this issue, we propose a new mechanism that utilizes mechanical force without causing high temperature. We carefully tune the geometry of gold nanoparticles to maximize the applied force on the membrane while minimizing the particle temperature. This work paves the way for further applications in cargo transportation.

Conference Presentation

Citation Download Citation

Ancheng Da, Jacob Krach, Yanan Chu, Yunbo Liu, and Somin Eunice Lee "Nanoplasmonic drill for optical injection", Proc. SPIE 11661, Plasmonics in Biology and Medicine XVIII, 116610N (8 March 2021); https://doi.org/10.1117/12.2578373

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