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8 March 2021 Mid-IR laser-based polarimetric imaging for polymeric and biological applications
Yamuna Phal, Kevin Yeh, Rohit Bhargava
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Proceedings Volume 11656, Advanced Chemical Microscopy for Life Science and Translational Medicine 2021; 1165619 (2021) https://doi.org/10.1117/12.2579099
Event: SPIE BiOS, 2021, Online Only
Abstract
Infrared polarimetry is a powerful label-free diagnostic tool to study the molecular alignment and organization in biological tissues and cells. Similar to absorbance images which capture intensity information, polarimetric imaging is essential for capturing the polarization states of the light intensity. Recent advancements in the development of Quantum Cascade Lasers (QCL) sources have opened new avenues in IR imaging with high spatial and spectral resolution while enabling drastic increases in imaging speeds than a corresponding FT-IR approach. We demonstrate improved performance in terms of fast and comprehensive polarimetric image acquisition using a custom-built QCL microscope with point mapping design.
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Yamuna Phal, Kevin Yeh, and Rohit Bhargava "Mid-IR laser-based polarimetric imaging for polymeric and biological applications", Proc. SPIE 11656, Advanced Chemical Microscopy for Life Science and Translational Medicine 2021, 1165619 (8 March 2021); https://doi.org/10.1117/12.2579099
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KEYWORDS
Polarimetry
Polymers
Mid-IR
Laser applications
Infrared imaging
Quantum cascade lasers
Microscopes
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