Anamorphic detection for adaptive optics line-scan OCT

Vimal Prabhu Pandiyan; Xiaoyun Jiang; James Kuchenbecker; Ramkumar Sabesan

doi:10.1117/12.2583274

5 March 2021 Anamorphic detection for adaptive optics line-scan OCT

Vimal Prabhu Pandiyan, Xiaoyun Jiang, James Kuchenbecker, Ramkumar Sabesan

Proceedings Volume 11623, Ophthalmic Technologies XXXI; 1162309 (2021) https://doi.org/10.1117/12.2583274
Event: SPIE BiOS, 2021, Online Only

Abstract

We introduce an anamorphic detection paradigm to optimize spatial and spectral resolution in adaptive optics line-scan OCT, wherein an improved light collection efficiency and signal roll-off compared to traditional methods was demonstrated. The benefits for in vivo imaging were exemplified by retrieving nanometer-scale light-induced optical path length dynamics at high speed in individual cones. The high speed, sensitivity and cellular-scale resolution of the resulting adaptive optics line-scan OCT instrument offers a robust and sensitive biomarker for retinal function in health and disease.

Conference Presentation

Citation Download Citation

Vimal Prabhu Pandiyan, Xiaoyun Jiang, James Kuchenbecker, and Ramkumar Sabesan "Anamorphic detection for adaptive optics line-scan OCT", Proc. SPIE 11623, Ophthalmic Technologies XXXI, 1162309 (5 March 2021); https://doi.org/10.1117/12.2583274

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