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24 April 2020 Toward cancer treatment using terahertz radiation: demethylation of cancer cells
Joo-Hiuk Son, Hwayeong Cheon
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Proceedings Volume 11390, Next-Generation Spectroscopic Technologies XIII; 1139002 (2020) https://doi.org/10.1117/12.2557655
Event: SPIE Defense + Commercial Sensing, 2020, Online Only
Abstract
Carcinogenesis involves DNA methylation, a primary alteration in DNA, in the development of cancer before genetic mutation. Because abnormal DNA methylation is found in most cancer cells, the assessment and manipulation of DNA methylation using terahertz radiation can be a novel optical method to detect and control cancer. By directly observing the methylation via terahertz spectroscopy at approximately 1.65 THz, this epigenetic chemical change can be manipulated to the state of demethylation using high-power terahertz radiation. Demethylation of cancer DNA is a key issue in epigenetic cancer therapy, and our results may lead to the treatment of cancer using electromagnetic waves.
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Joo-Hiuk Son and Hwayeong Cheon "Toward cancer treatment using terahertz radiation: demethylation of cancer cells", Proc. SPIE 11390, Next-Generation Spectroscopic Technologies XIII, 1139002 (24 April 2020); https://doi.org/10.1117/12.2557655
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KEYWORDS
Cancer
Terahertz radiation
Oncology
Blood
Breast cancer
Lymphoma
Leukemia
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