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Diffuse correlation spectroscopy (DCS) is an established diffuse optical technique that uses the analysis of temporal speckle intensity fluctuations to measure blood flow in tissue. DCS has been shown to be an effective monitor of cerebral blood flow in many neuro-monitoring applications, though still suffers from depth sensitivity issues. Recent studies have shown that moving to 1064 nm when making DCS measurements improves SNR and sensitivity to depth, but detector challenges have slowed the change to that wavelength. Here, we present on a multipixel, interferometric DCS (iDCS) system that improves measurement capabilities at this wavelength.
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Mitchell B. Robinson, Davide Tamborini, Adriano Peruch, Stefan A. Carp, Maria Angela Franceschini, "Multi-element interferometric diffuse correlation spectroscopy at 1064 nm (Conference Presentation)," Proc. SPIE 11253, Biomedical Applications of Light Scattering X, 112530I (10 March 2020); https://doi.org/10.1117/12.2546350