Quantitative phase digital holographic microscopy combined with stem cell technology for identifying cell biomarkers of neurodevelopmental brain disorders including schizophrenia (Conference Presentation)

Pierre P. Marquet; François Paquet-Mercier; Chloé Martel; Catherine Giroux; Carine Ben Adiba; Ana-Sofia Correia; Émile Rioux Pellerin; Jean-Xavier Giroux; Marie-Eve Crochetière; Erik Bélanger; Pascal Jourdain

doi:10.1117/12.2546407

11 March 2020 Quantitative phase digital holographic microscopy combined with stem cell technology for identifying cell biomarkers of neurodevelopmental brain disorders including schizophrenia (Conference Presentation)

Pierre P. Marquet, François Paquet-Mercier, Chloé Martel, Catherine Giroux, Carine Ben Adiba, Ana-Sofia Correia, Émile Rioux Pellerin, Jean-Xavier Giroux, Marie-Eve Crochetière, Erik Bélanger, Pascal Jourdain

Author Affiliations +

Proceedings Volume 11249, Quantitative Phase Imaging VI; 112490V (2020) https://doi.org/10.1117/12.2546407
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

The recent developments in stem cell biology especially the generation of induced pluripotent stem cells (iPSCs) has made possible the development of in vitro cellular models of developmental brain disorders including schizophrenia. Within this framework, we will present how quantitative phase imaging and in particular quantitative phase digital holographic microscopy (QP-DHM), as a label-free technique is able to study these in vitro cellular models and identify both some pathophysiological processes and cell biomarkers related to developmental brain disorders. This will be illustrated by the exploration with QP-DHM of human neuronal networks derived from iPSCs coming from patients suffering from schizophrenia.

Conference Presentation

Citation Download Citation

Pierre P. Marquet, François Paquet-Mercier, Chloé Martel, Catherine Giroux, Carine Ben Adiba, Ana-Sofia Correia, Émile Rioux Pellerin, Jean-Xavier Giroux, Marie-Eve Crochetière, Erik Bélanger, and Pascal Jourdain "Quantitative phase digital holographic microscopy combined with stem cell technology for identifying cell biomarkers of neurodevelopmental brain disorders including schizophrenia (Conference Presentation)", Proc. SPIE 11249, Quantitative Phase Imaging VI, 112490V (11 March 2020); https://doi.org/10.1117/12.2546407

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available