Comparing cervical maturation in preterm and term birth mouse models with Raman spectroscopy (Conference Presentation)

Rekha Gautam; Jennifer Herington; Naoko Brown; Wilson Adam; Jackson H. Rogers; Jen Bateman; Christine O'Brien; Jeff Reese; Anita Mahadevan-Jansen

doi:10.1117/12.2551333

9 March 2020 Comparing cervical maturation in preterm and term birth mouse models with Raman spectroscopy (Conference Presentation)

Rekha Gautam, Jennifer Herington, Naoko Brown, Wilson Adam, Jackson H. Rogers, Jen Bateman, Christine O'Brien, Jeff Reese, Anita Mahadevan-Jansen

Author Affiliations +

Proceedings Volume 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry; 112360W (2020) https://doi.org/10.1117/12.2551333
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Preterm birth (PTB), when defined as labor before 37 weeks of gestation, affects approximately 1 out of every 10 births in the United States, leading to high rates of mortality. Complete understanding of the mechanism of PTB requires non-invasive, multi-modal techniques that can provide information about the cascade of labor onset. This study compares the cervical remodeling in wild-type term and induced preterm mouse models using Raman spectroscopy. This study demonstrates the potential of Raman spectroscopy as a non-invasive, real-time in-vivo modality to understand cervix remodeling, thus guiding future studies to improve reproductive and neonatal outcomes.

Conference Presentation

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Rekha Gautam, Jennifer Herington, Naoko Brown, Wilson Adam, Jackson H. Rogers, Jen Bateman, Christine O'Brien, Jeff Reese, and Anita Mahadevan-Jansen "Comparing cervical maturation in preterm and term birth mouse models with Raman spectroscopy (Conference Presentation)", Proc. SPIE 11236, Biomedical Vibrational Spectroscopy 2020: Advances in Research and Industry, 112360W (9 March 2020); https://doi.org/10.1117/12.2551333

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