Video-rate multi-exposure laser speckle contrast imaging for real-time microcirculation blood flow assessment in skin (Conference Presentation)

Martin Hultman; Ingemar Fredriksson; Marcus Larsson; Tomas Strömberg

doi:10.1117/12.2541659

6 March 2020 Video-rate multi-exposure laser speckle contrast imaging for real-time microcirculation blood flow assessment in skin (Conference Presentation)

Martin Hultman, Ingemar Fredriksson, Marcus Larsson, Tomas Strömberg

Author Affiliations +

Proceedings Volume 11211, Photonics in Dermatology and Plastic Surgery 2020; 112110Y (2020) https://doi.org/10.1117/12.2541659
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

This talk highlights a novel instrument for real-time video-rate imaging of microcirculation blood flow. The instrument utilizes multi-exposure laser speckle contrast imaging (MELSCI) with a high-speed camera, custom integrated electronics, and machine learning for massive computational bandwidth. This instrument enables, for the first time, continuous in vivo imaging of blood flow at frame rates sufficiently high to track dynamic changes, with perfusion estimates strongly correlated with that of laser Doppler flowmetry (LDF). This is an important step enabling a better understanding of the role of the microcirculation in several cardiovascular diseases. A pilot study on healthy subjects is presented.

Conference Presentation

Citation Download Citation

Martin Hultman, Ingemar Fredriksson, Marcus Larsson, and Tomas Strömberg "Video-rate multi-exposure laser speckle contrast imaging for real-time microcirculation blood flow assessment in skin (Conference Presentation)", Proc. SPIE 11211, Photonics in Dermatology and Plastic Surgery 2020, 112110Y (6 March 2020); https://doi.org/10.1117/12.2541659

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