Generation and monitoring of cavitation with an optical resolution photoacoustic microscope

G. Paltauf; R. Nuster

doi:10.1117/12.2526717

19 July 2019 Generation and monitoring of cavitation with an optical resolution photoacoustic microscope

G. Paltauf, R. Nuster

Proceedings Volume 11077, Opto-Acoustic Methods and Applications in Biophotonics IV; 110770X (2019) https://doi.org/10.1117/12.2526717
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

An optical resolution photoacoustic microscopy (OR-PAM) setup was used to generate transient cavitation on a strongly absorbing target. The cavitation bubble dynamics were monitored with an optical probe beam, which was guided collinearly and confocally with the excitation laser pulses. Simultaneously, the acoustic transients occurring during initiation and collapse of the bubbles were measured with a probe beam deflection method. With 25 nJ pulse energy, cavitation bubbles of 15 to 20 μm maximum diameter were generated around a carbon fiber. Bubble properties, such as its expansion speed and lifetime were observed with the optical signal, which showed oscillations caused by interference after reflection at the bubble walls. The acoustic signal provided additional measurements of the bubble lifetime. The proposed method can be used to investigate the influence of cavitation on the acoustic OR-PAM signal and to monitor theranostic applications of cavitation bubbles.

Citation Download Citation

G. Paltauf and R. Nuster "Generation and monitoring of cavitation with an optical resolution photoacoustic microscope", Proc. SPIE 11077, Opto-Acoustic Methods and Applications in Biophotonics IV, 110770X (19 July 2019); https://doi.org/10.1117/12.2526717

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available