Non-invasive spectroscopic method of glucose concentration detemination in human blood: mathematical description

B. S. Gurevich; V. V. Shapovalov; S. Y. Dudnikov; I. G. Zagorsky; A. V. Belyaev

doi:10.1117/12.2526493

11 July 2019 Non-invasive spectroscopic method of glucose concentration detemination in human blood: mathematical description

B. S. Gurevich, V. V. Shapovalov, S. Y. Dudnikov, I. G. Zagorsky, A. V. Belyaev

Author Affiliations +

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 110741V (2019) https://doi.org/10.1117/12.2526493
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

The proposed method relates to spectroscopic ones and is based on the measurement of the intensity of the absorbed irradiation when it passes through the blood-containing organ of a patient. This way of non-invasive determination of glucose contents in human blood was proposed far ago but the reason of its absence in the market is the non-solved problem of the irradiation part definition which is absorbed just by glucose but not by the other absorbing components of the human organ. This problem solution includes measurements of irradiation absorption at numerous wavelengths of irradiation and application of specific mathematical apparatus which we propose to apply for this method. The mathematical calculations include the solution of linear equations system with light intensity parts which are absorbed by different absorbing components as variables. The number of equations id equal to the amount of absorbing components and the number of wavelengths at which the measurements must be performed. The calculations allowing to transfer the part of absorbed light into glucose concentration also are listed

Citation Download Citation

B. S. Gurevich, V. V. Shapovalov, S. Y. Dudnikov, I. G. Zagorsky, and A. V. Belyaev "Non-invasive spectroscopic method of glucose concentration detemination in human blood: mathematical description", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110741V (11 July 2019); https://doi.org/10.1117/12.2526493

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