Differentiation of collagens I, II, and III by second order susceptibility imaging

Sheng-Lin Lee; Chiu-Mei Hsueh; Ya-Der Huang; Hsuan-Shu Lee; Chen-Yuan Dong

doi:10.1117/12.2507168

22 February 2019 Differentiation of collagens I, II, and III by second order susceptibility imaging

Sheng-Lin Lee, Chiu-Mei Hsueh, Ya-Der Huang, Hsuan-Shu Lee, Chen-Yuan Dong

Proceedings Volume 10882, Multiphoton Microscopy in the Biomedical Sciences XIX; 1088235 (2019) https://doi.org/10.1117/12.2507168
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Second order susceptibility (SOS) microscopy is used as a contrast mechanism for distinguishing types I and III collagen in tissues. In addition, relative proportion of collagen type was determined by analyzing the histograms of SOS ratios. Our results show that second order susceptibility is an effective metric for differentiating types I and III collagen without extrinsic labeling.

Citation Download Citation

Sheng-Lin Lee, Chiu-Mei Hsueh, Ya-Der Huang, Hsuan-Shu Lee, and Chen-Yuan Dong "Differentiation of collagens I, II, and III by second order susceptibility imaging", Proc. SPIE 10882, Multiphoton Microscopy in the Biomedical Sciences XIX, 1088235 (22 February 2019); https://doi.org/10.1117/12.2507168

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available