Phase-sensitive OCT in monitoring of slow-rate strains in laser tissue reshaping

V. Y. Zaitsev; L. A. Matveev; A. L. Matveyev; A. A. Sovetsky; G. V. Gelikonov; O. I. Baum; A. I. Omelchenko; A. V. Yuzhakov; E. N. Sobol

doi:10.1117/12.2508832

21 February 2019 Phase-sensitive OCT in monitoring of slow-rate strains in laser tissue reshaping

V. Y. Zaitsev, L. A. Matveev, A. L. Matveyev, A. A. Sovetsky, G. V. Gelikonov, O. I. Baum, A. I. Omelchenko, A. V. Yuzhakov, E. N. Sobol

Author Affiliations +

Proceedings Volume 10880, Optical Elastography and Tissue Biomechanics VI; 108800K (2019) https://doi.org/10.1117/12.2508832
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

We present a realization of real-time OCT-based strain mapping by estimating interframe phase-variation gradient using the developed "vector" method. This technique allows for mapping both fairly fast and large, as well as rather small strains, slowly-varying on intervals ~tens of minutes. Optimization of interframe interval for improving signal-to-noise ratio is discussed and experimentally demonstrated. Ultimate stability of strain estimation with the designed OCT setup is experimentally estimated using stable phantoms. Examples of spatially resolved maps of slowly-varying strains are demonstrated. The developed methods can be used in emerging techniques of laser-assisted modification of collagenous tissues (e.g., for such perspective application as fabrication of cartilaginous implants).

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V. Y. Zaitsev, L. A. Matveev, A. L. Matveyev, A. A. Sovetsky, G. V. Gelikonov, O. I. Baum, A. I. Omelchenko, A. V. Yuzhakov, and E. N. Sobol "Phase-sensitive OCT in monitoring of slow-rate strains in laser tissue reshaping ", Proc. SPIE 10880, Optical Elastography and Tissue Biomechanics VI, 108800K (21 February 2019); https://doi.org/10.1117/12.2508832

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