Tomographic flow cytometry of circulating human breast adenocarcinoma cells

Pasquale Memmolo; Massimiliano M. Villone; Francesco Merola; Martina Mugnano; Lisa Miccio; Pier Luca Maffettone; Pietro Ferraro

doi:10.1117/12.2319591

7 September 2018 Tomographic flow cytometry of circulating human breast adenocarcinoma cells

Pasquale Memmolo, Massimiliano M. Villone, Francesco Merola, Martina Mugnano, Lisa Miccio, Pier Luca Maffettone, Pietro Ferraro

Author Affiliations +

Proceedings Volume 10834, Speckle 2018: VII International Conference on Speckle Metrology; 108341W (2018) https://doi.org/10.1117/12.2319591
Event: SPECKLE 2018: VII International Conference on Speckle Metrology, 2018, Janów Podlaski, Poland

Abstract

We demonstrate the non-invasive investigation of circulating human breast adenocarcinoma cells in microfluidic environment by implementing the full-angle tomographic phase microscopy (TPM). The proposed approach lies in a completely passive optical system, i.e. avoiding mechanical scanning or multi-direction probing of the sample and exploiting the engineered rolling of cells while they are flowing along a microfluidic channel.

Citation Download Citation

Pasquale Memmolo, Massimiliano M. Villone, Francesco Merola, Martina Mugnano, Lisa Miccio, Pier Luca Maffettone, and Pietro Ferraro "Tomographic flow cytometry of circulating human breast adenocarcinoma cells", Proc. SPIE 10834, Speckle 2018: VII International Conference on Speckle Metrology, 108341W (7 September 2018); https://doi.org/10.1117/12.2319591

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