Blood flow oscillations as a signature of microvascular abnormalities

Elena V. Zharkikh; Irina A. Mizeva; Irina I. Makovik; Viktor V. Dremin; Evgeny A. Zherebtsov; Elena V. Potapova; Andrey V. Dunaev

doi:10.1117/12.2307476

17 May 2018 Blood flow oscillations as a signature of microvascular abnormalities

Elena V. Zharkikh, Irina A. Mizeva, Irina I. Makovik, Viktor V. Dremin, Evgeny A. Zherebtsov, Elena V. Potapova, Andrey V. Dunaev

Author Affiliations +

Proceedings Volume 10685, Biophotonics: Photonic Solutions for Better Health Care VI; 106854C (2018) https://doi.org/10.1117/12.2307476
Event: SPIE Photonics Europe, 2018, Strasbourg, France

Abstract

Laser Doppler flowmetry (LDF) was utilized for blood ow measurements. Wavelet analysis was used to identify spectral characteristics of the LDF signal in patients with rheumatic diseases and diabetes mellitus. Baseline measurements were applied for both pathological groups. Blood flow oscillations analyses were performed by means of the wavelet transform.

Higher baseline perfusion was observed in both pathological groups in comparison to controls. Differences in the spectral properties between the groups studied were revealed. The results obtained demonstrated that spectral properties of the LDF signal collected in basal conditions may be the signature of microvasculature functional state.

Citation Download Citation

Elena V. Zharkikh, Irina A. Mizeva, Irina I. Makovik, Viktor V. Dremin, Evgeny A. Zherebtsov, Elena V. Potapova, and Andrey V. Dunaev "Blood flow oscillations as a signature of microvascular abnormalities", Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 106854C (17 May 2018); https://doi.org/10.1117/12.2307476

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