Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging

Yuri Belotti; Michael Conneely; Tianjun Huang; Stephen McKenna; Ghulam Nabi; David McGloin

doi:10.1117/12.2284553

28 July 2017 Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging

Yuri Belotti, Michael Conneely, Tianjun Huang, Stephen McKenna, Ghulam Nabi, David McGloin

Proceedings Volume 10413, Novel Biophotonics Techniques and Applications IV; 1041305 (2017) https://doi.org/10.1117/12.2284553
Event: European Conferences on Biomedical Optics, 2017, Munich, Germany

Abstract

We demonstrate a single channel hydrodynamic stretching microfluidic device that relies on high-speed imaging to allow repeated dynamic cell deformation measurements. Experiments on prostate cancer cells suggest richer data than current approaches.

Citation Download Citation

Yuri Belotti, Michael Conneely, Tianjun Huang, Stephen McKenna, Ghulam Nabi, and David McGloin "Microfluidics-based, time-resolved mechanical phenotyping of cells using high-speed imaging", Proc. SPIE 10413, Novel Biophotonics Techniques and Applications IV, 1041305 (28 July 2017); https://doi.org/10.1117/12.2284553

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